Carry a small package your players can execute in both directions. The call sheet changes the priority of those plays; it does not ask the team to learn a new offense for every down.
Coach to the actual line to gain. On long yardage, an attainable completion and yards after the catch are usually better bets than turning a practiced quick concept into an improvised deep throw.
Script down-and-distance periods in practice. Players should hear the situation, understand the reason for the call, and know where the ball must finish before the snap.
Confirm local league rules. Player count, no-run zones, rush timing, blocking restrictions, and punt options can all change the correct decision.